On the basis of a survey carried out, in 1999-2000, in randomly selected urban areas with at least 10% Russian residents of ten ethnic republics of the Federation of Russia (Karelia, Komi, Tatarstan, Bashkortostan, Udmurtia, Adygea, Dagestan, Kabardo-Balkaria, Sakha-Yakutia, and Tuva), this study examines the oscillations of popular support for separatism among Russians and non-Russian titular nationalities. Although non-indicative for rural areas, the overall result highlights the lack of evidence of majority support for separatism in any of the selected republics ― maximum support being reached in Sakha-Yakutia (52% of the titular nation and 31% of the Russians), Tatarstan (51% and 21%), and Tuva (50% of titular nationals but in this case only 8% of the Russians). The authors also observe that if negative intergroup relations contribute to support for separatism among titular groups, they conversely reduce it among Russians. In contrast, indicators of prosperity of the republic predict support for separatism among both titular groups and Russians. Russian supporters of separatism are across the board young, lower educated, and believe in the economic prospects of their republic. They also know that the Russian group is large enough in the republic to remain dominant in case of secession. The picture for titular separatism is substantively different, with supporters also young, though not necessarily lower educated, and with confrontational motivations for separatism.